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How Intentional Breathing Enhances Mind, Body, and Spirit

Inhale… and Exhale. The Science of Breathwork

Written by
@Ewa Kasprzak
|
Published on
March 16, 2025

Breathwork has been getting a lot of buzz lately, and for good reason! This simple but powerful practice can upgrade your mental and physical well-being. But what’s actually happening inside our bodies when we focus on our breath?

Let’s dive into the science behind breathwork and why it’s worth adding to your daily routine!

What Happens at the Cellular Level

Every breath you take is more than just air moving in and out—it’s a biochemical process essential for keeping your body running smoothly. When we inhale, our lungs fill with oxygen (O₂), which is then transported by red blood cells to our tissues. There, oxygen is used to produce adenosine triphosphate (ATP), the molecule that fuels almost every function in our body.

As we exhale, we release carbon dioxide (CO₂), a waste product of cellular metabolism. The balance of O₂ and CO₂ is critical—too much CO₂ can make the blood acidic, while too little can cause dizziness or fainting (Noble & Hochman, 2019). Breathwork helps regulate this delicate balance, improving oxygen efficiency and enhancing overall cellular function.

Additionally, controlled breathing increases the production of nitric oxide (NO), a molecule that relaxes blood vessels and improves circulation (Lundberg et al., 2008). This means better blood flow to the brain and organs, leading to improved cognitive and physical performance.

How Breathwork Affects the Physical Body

Now that we understand how breathwork affects us at the cellular level, let’s look at its impact on our physical body. Breathing directly impacts our overall health. A study by Balban et al. (2023) in Cell Reports Medicine found that short, structured breathwork sessions can lower stress, slow down heart rate, and promote relaxation.

Cyclic Sighing and PNS Activation

One of the most effective techniques is cyclic sighing, which emphasises longer exhales to activate the parasympathetic nervous system (PNS)—the part of the autonomic nervous system responsible for rest and digestion. Activating the PNS helps lower blood pressure, reduce inflammation, and enhance recovery from stress.

Heart Rate Variability and Stress Adaptation

Another key benefit of breathwork is its impact on heart rate variability (HRV), a measure of how well your body adapts to stress. Higher HRV is associated with better cardiovascular health, reduced risk of chronic illness, and improved athletic performance. Slow, deep breathing has been shown to increase HRV and stabilize the body’s response to stress (Jerath et al., 2015).

ChillsnSip Plunge Event (breathing practive) April 2024.

The Mental Health Benefits of Breathwork

Breathwork doesn’t just relax the body—it has a profound effect on mental health.

A study by Fincham, Strauss, and Cavanagh (2023) in Scientific Reports examined the effects of coherent breathing, a technique where you maintain a steady breath rate of around six breaths per minute. Their research found that this practice significantly reduced anxiety and improved emotional well-being.

Scientific Evidence

A broader meta-analysis by Fincham et al. (2023) confirmed that breathwork is a reliable tool for reducing stress, enhancing resilience, and improving mood. Additionally, research by Zaccaro et al. (2018) showed that slow breathing techniques help regulate emotions, alleviate symptoms of PTSD, and improve overall mental clarity.

Neural Mechanisms in Breathwork

One reason breathwork is so effective for mental health is its influence on the prefrontal cortex, the part of the brain responsible for decision-making and emotional regulation. By controlling our breath, we can shift brain activity away from the stress-driven amygdala and into the rational, calming areas of the brain.

This is especially useful for processing psychological trauma. Deep, controlled breathing can help regulate the limbic system, the part of the brain that processes emotions and memories. Techniques like holotropic breathing and rebirthing breathwork have been used to access repressed emotions, providing a safe way to release stored trauma and promote healing. Many practitioners describe these experiences as deeply transformative, fostering a sense of peace, connection, and self-discovery.

Easy Breathwork Techniques to Try

Want to add breathwork to your routine? Here are a few simple methods backed by science:

  • Cyclic Sighing – Inhale deeply through your nose, take a short second inhale, then slowly exhale through your mouth. Repeat for 5–10 minutes\
  • Coherent Breathing – Breathe in for 5 seconds and out for 5 seconds, keeping a steady rhythm for 10–20 minutes
  • Box Breathing – Inhale for 4 seconds, hold for 4 seconds, exhale for 4 seconds, and hold again for 4 seconds. Repeat for a few minutes

Breathwork isn’t just hype—it’s a science-backed way to feel better both mentally and physically. By practicing simple breathing exercises, you can reduce stress, improve your mood, and give your nervous system the reset it needs.

Frequently Asked Questions (FAQ)

What is breathwork?

Breathwork is the practice of intentional breathing techniques that enhance mental and physical well-being by optimizing the balance of oxygen and carbon dioxide, among other benefits.

How does cyclic sighing benefit my body?

Cyclic sighing helps activate the parasympathetic nervous system, which lowers blood pressure, reduces inflammation, and promotes relaxation.

Can breathwork improve mental health?

Yes, studies—such as the one by Fincham, Strauss, & Cavanagh (2023)—have shown that techniques like coherent breathing can reduce anxiety, improve emotional well-being, and help regulate brain functions involved in stress.

How often should I practice breathwork?

Incorporating breathwork into your daily routine for even 5–10 minutes can yield noticeable benefits over time.

Resources:

Balban, M. Y., et al. (2023). Brief structured respiration practices enhance mood and reduce physiological arousal. Cell Reports Medicine, 4(1), 100895. https://doi.org/10.1016/J.XCRM.2022.100895

Fincham, G. W., Strauss, C., & Cavanagh, K. (2023). Effect of coherent breathing on mental health and wellbeing: a randomised placebo-controlled trial. Scientific Reports, 13(1), 1–12. https://doi.org/10.1038/s41598-023-49279-8

Fincham, G. W., et al. (2023). Effect of breathwork on stress and mental health: A meta-analysis of randomised-controlled trials. Scientific Reports, 13(1), 1–14. https://doi.org/10.1038/s41598-022-27247-y

Jerath, R., Edry, J. W., Barnes, V. A., & Jerath, V. (2015). Physiology of long pranayamic breathing: Neural, respiratory, and cardiovascular correlates. Frontiers in Psychology, 6, 763. https://doi.org/10.3389/fpsyg.2015.00763

Zaccaro, A., et al. (2018). How breath-control can change your life: A systematic review on psychophysiological correlates of slow breathing. Frontiers in Human Neuroscience, 12, 353. https://doi.org/10.3389/fnhum.2018.00353

@Ewa Kasprzak

Female Health and Wellbeing 📝I talk about: Female Reproductive Health | Science | Hormones | Ayurveda | Yoga | Spirituality
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